+ How do I receive treatment?

Educator Therapy is not yet commercially available. We are currently undergoing the FDA approval process and aim to be commercially approved within the next three years (2023).

+ Are there Educator Therapy clinical trials?

We are accepting applicants for Type 1 Diabetes and Alopecia Areata clinical trials in New Jersey. The Alopecia trial will require 10 in-person visits split between New Jersey and Connecticut. The Type 1 Diabetes trial will require 10 in-person visits to our partner facility in New Jersey. Please email connect@thronebio.com to request the application form.

+ What diseases are treated by Educator Therapy?

Educator Therapy primarily treats Type 1 Diabetes and Alopecia Areata. Additional autoimmune diseases have been tested with Educator Therapy: Type 2 Diabetes, Alopecia Totalis, Alopecia Universalis, Lupus, Psoriasis, Graves’ Disease, Hashimoto’s Disease, Scleroderma, Fibrosis, and Sjogren’s Syndrome. Further research is being developed to use Educator Therapy to treat additional incurable diseases.

+ What is Stem Cell Educator Therapy?

Stem Cell Educator Therapy (i.e. Educator Therapy) is an in vitro process where a patient’s white blood cells are circulated through a Stem Cell Educator device that is coated with umbilical-cord blood stem cells, CB-SCs. As this circulation occurs, the patient’s white blood cells (MNCs) intercept the CB-SC’s communications, re-educating the cells back to their pre-diseased state. This process then circulates only the ‘educated’ white blood cells back into the patient (the CB-SCs never leave the Stem Cell Educator device). The newly ‘educated’ cells then educate other defective cells in the patient’s body on who to fight and who to protect. This immune reset allows the patient’s immune system to fight for its healing the way it was initially designed.

Educator Therapy does not introduce stem cells or reagents into patients, ensuring 100% immune acceptance and zero risk of rejection.

+ What are human umbilical-cord blood stem cells (CB-SCs)?

Dr. Yong Zhao discovered and patented the human umbilical-cord blood stem cell (CB-SC) in 2005. He later found that CB-SCs are also found in human adult blood, known as peripheral blood insulin-producing stem cells (PB-SCs or PB-IPC). CB-SCs are more powerful than any other multipotent stem cells. They completely eliminate the requirement for stem cell matching because they have very low immunogenicity. Stem Cell Educator Therapy is the only technology in the world licensed to use these stem cells.

+ What is the treatment process?

Depending on the facility, the Stem Cell Educator Therapy may be administered in one of two ways: closed-looped treatment or open-looped treatment. Both treatments provide a patient with their own blood separator and Educator device.

For closed-looped treatment, the patient’s blood is cycled from one arm to a blood separator (apheresis machine) where their white bloods are separated (the red blood cells are immediately returned to the body). Next, their white blood cells are passed through the Stem Cell Educator device where they are treated (re-educated) and then directly returned to the patient’s body through the other arm. This continuous loop lasts for 8 to 9 hours.

For open-looped treatment, the process is split between two days. On day one, the patient’s blood is drawn and 200 milliliters of white blood cells are separated over the course of 4 hours (the red blood cells are immediately returned to the body). Overnight, the white blood cells are incubated in the Stem Cell Educator device for 17 hours. On day two, the patient returns to the facility and the treated white blood cells are infused back into their body.

+ Does Educator Therapy use stem cell injections or transplantations?

Zero stem cell injections, transplantations, or blood transfusions occur in Educator Therapy. Instead, Educator Therapy utilizes an in vitro method where CB-SCs are permanently contained in the patient's personal Educator Device. This ensures immune acceptance and eliminates any risks of rejection, as the only cells entering the patient's body are their own white blood cells that have been treated by the CB-SCs.

+ Does Educator Therapy account for ethical and religious considerations?

Yes, zero stem cells from animals or aborted fetuses are used in Educator Therapy, as these treatment methods result in safety risks, ethical and religious concerns.

+ Does Educator Therapy require genetic matching?

No, Educator Therapy does not require genetic matching. CB-SCs, the multipotent stem cells used in Educator Therapy, have very low immunogenicity and therefore eliminate the requirement for genetic stem cell matching.

+ Where does Educator Therapy get the umbilical-cord blood?

Throne Biotechnologies partners with domestic (umbilical) cord blood banks. All cord blood provided to Throne Biotechnologies Inc. for Educator Therapy is thoroughly screened.

+ Can I use my personal stored cord blood?

No, Educator Therapy does not use any stored cord blood. The freezing process that occurs when cord blood is stored results in a 20% loss of stem cells. For this reason, Educator Therapy only uses fresh umbilical cord blood obtained from domestic cord blood banks. There is no benefit to using personal stored cord blood because CB-SCs eliminate the need for genetic matching in Educator Therapy’s in vitro process.

+ Will Educator Therapy cure my autoimmune disease?

Our clinical trials provide powerful evidence that a single treatment with Educator Therapy may provide lasting reversal of autoimmunity. Type 1 and Type 2 Diabetes patients have experienced both significant reduction and complete elimination of insulin injections. Alopecia patients have experienced significant hair regrowth. These are just a few examples of the benefits of Educator Therapy.

Autoimmunity is complex because every individual’s body responds differently. Patients must recognize their role in maintaining a healthy lifestyle post-treatment to foster their renewed autoimmunity.

+ Does Educator Therapy require one treatment or multiple treatments?

Educator Therapy can provide lasting reversal autoimmunity through one treatment. Most patients receive one to two treatments.

+ How long does one treatment of Educator Therapy take?

One treatment of Educator Therapy will take roughly 8 to 9 hours, often split between two days.

+ I have had Educator Therapy. What is next?

After treatment, patients are encouraged to monitor their normative response (i.e. clinical outcomes) through their family doctors and/or endocrinologist. As they monitor their normative responses post-treatment, they can adjust any typical dosages based on their family doctor’s recommendations.

+ Where can I find scientific publications supporting the efficacy and effectiveness of Educator Therapy?

Dr. Zhao has successfully published multiple peer-reviewed clinical journals detailing the safety and effectiveness of Stem Cell Educator Therapy. Click here to be redirected to Throne's Journal Publications page.

+ What have clinical trials proven about Educator Therapy?

Clinical trials have proven Educator Therapy to be safe, non-invasive and effective with one treatment producing lasting improvement in metabolic control and immune modulation. Click here to be redirected to Throne's Clinical Application page.

+ Has the U.S. Food and Drug Administration (FDA) approved Educator Therapy?

Throne Biotechnologies has received two approvals for the second of three clinical trial phases from the FDA. The third phase of clinical trials is anticipated to conclude within the next three years, at which point Educator Therapy will be FDA approved for commercialization. Please click here to be redirected to the FDA’s website where you can read further about the development and approval process.

+ Is Educator Therapy safe?

Yes, Educator Therapy is safe and non-invasive. Unlike any other stem cell treatment, Educator Therapy does not introduce stem cells or reagents into patients, ensuring 100% immune acceptance and zero risk of rejection.

+ What are the risks of Educator Therapy?

As Educator Therapy is a non-invasive treatment with zero stem cells or reagents introduced into the patient, there are no risks or safety concerns associated with it.

+ Are there any immediate or long-term side effects of receiving Educator Therapy?

Individuals who undergo Educator Therapy experience minimal to zero side effects. Minimal side effects include slight discomfort from the apheresis process (blood draw).